Adrenal Hormones
The Adrenals are two small glands; one located above each kidney, each weighing three to five grams. Each adrenal gland is composed of two separate functional entities. The outer zone, or cortex, accounts for 80% to 90% of the gland, and secretes adrenal steroids (cortisol, dehydroepiandrosterone (DHEA), and aldosterone).
The inner zone, or medulla, comprises 10% to 20% of the gland, and secretes adrenaline, nor-adrenaline, epinephrine, nor-epinephrine, called catecholamines. Cortisol, DHEA and adrenaline are the three adrenal stress hormones. DHEA declines dramatically with age.
DHEA Levels Related to Age
DHEA is the 2nd most abundant steroid in the body (Cholesterol is number 1). Decreased levels of DHEA maybe associated with diabetes, Alzheimer's disease, age associated memory impairment (AAMI), and senility. The human adrenal gland does not secrete its steroid hormones at a constant level throughout the day. The hormones are actually released in a cycle with the highest value in the morning and lowest at night.
This 24-hour cycle is called the circadian rhythm. An abnormal adrenal rhythm can influence many functions of the body.
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